ArticleResults and problems in cell differentiation2026
How Touch Triggers Mechanotransduction in Cutaneous Mechanoreceptors.
Article in Results and problems in cell differentiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Understanding the mechanotransduction mechanisms underlying the tactile dimension of skin aging remains an underexplored aspect of dermatological and neurosciences. This investigation introduces a novel mechanosensory responsiveness index, tactile acuity index (TAI), derived from a time-frequency analysis of friction-induced vibrations recorded during controlled touch interactions utilizing the wearable tactile acquisition device (WTAD). By decomposing tactile signals across frequency bands specific to Merkel, Meissner, Ruffini, and Pacinian mechanoreceptors, TAI quantifies both the amplitude and spectral organization of vibrational energy transmitted through the skin.In a first experimental phase, TAI exhibited a clear monotonic decline across seven grades of paper textures, confirming that smoother surfaces produce weaker and spectrally narrower mechanical stimulation, thereby reducing mechanoreceptor recruitment. The strongest correlations were observed for Ruffini (R
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