Evidence map›Paper›PMID 42223613›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Effect of tonsillar fossa suturing in adolescents and adults: a systematic review and meta-analysis.

Yi-Chan Lee, Li-Jen Hsin, Yi-Hsuan Lee, Yi-An Lu, Tuan-Jen Fang, Yao-Te Tsai, Shih-Chi Su, Cheng-Ming Luo, Hsueh-Yu Li

Abstract readSystematic ReviewMeta-Analysis
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In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yi-Chan Lee *Department of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, No. 222, Maijin Rd., Anle Dist., Keelung City, Taiwan.
Li-Jen HsinDepartment of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Yi-Hsuan LeeDepartment of Orthopedic Surgery, Buddhist Tzu-Chi General Hospital, Taipei, Taiwan.
Yi-An LuDepartment of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Tuan-Jen FangDepartment of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Yao-Te TsaiDepartment of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Shih-Chi SuWhole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan.
Cheng-Ming Luo *Department of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, No. 222, Maijin Rd., Anle Dist., Keelung City, Taiwan. lcm3647@gmail.com.
Hsueh-Yu Li *Department of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTonsillectomy is one of the most frequently performed surgical procedures in otolaryngology. Postoperative hemorrhage (PTH) and pain remain major concerns, particularly in adolescents and adults, in whom complications are more severe. The role of tonsillar fossa suturing after tonsillectomy in reducing these complications is still controversial.

methodsWe conducted a comprehensive search of PubMed, Embase, and the Cochrane Library for studies comparing tonsillectomy with suturing (TS) versus without suturing (TNS) in patients older than 10 years.

resultsSeven studies involving 3051 patients were included. Meta-analysis showed that TS significantly reduced the risk of overall PTH (odds ratio [OR], 0.329; 95% confidence interval [CI], 0.145-0.751), primary PTH (OR, 0.140; 95% CI, 0.036-0.540), secondary PTH (OR, 0.310; 95% CI, 0.174-0.552), and minor PTH (OR, 0.193; 95% CI, 0.086-0.429). No significant difference was observed for major PTH (OR, 0.550; 95% CI, 0.138-2.187). Regarding postoperative pain, a possible delayed difference was observed, with lower pain scores in the TS group on postoperative day 7 (mean difference [MD], - 1.646; 95% CI, - 3.202 to - 0.090), whereas scores on days 1, 2, 3, and 14 were comparable between groups.

conclusionThese findings suggest that, in adolescents and adults, TS is associated with a reduced risk of PTH. Pain-related outcomes were exploratory and based on limited data. To our knowledge, this is the first meta-analysis focused on this higher-risk population, providing evidence to inform surgical decision-making.

Indexed as

Palatine TonsilPostoperative HemorrhagePostoperative PainSuture TechniquesTonsillectomyAdolescentAdultHumansAdolescentAdultPain, postoperativePostoperative hemorrhageSuturesTonsillectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.