ArticleACS omega2026
Palladium Porphyrin-Modified Fibrin Hydrogel for Oxygen Sensing in Engineered Skin Tissue Applications.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Tissue engineering is transforming regenerative medicine by enabling the creation of functional tissue substitutes for in vitro research and therapeutic applications. Optimization of skin-engineered tissues would clearly be favored by local, real-time, and precise oxygen concentration measurements, as oxygen plays a fundamental role in cellular metabolism, survival, and tissue regeneration. This work presents a fluorescence-based oxygen biosensor that is chemically stable and integrated into fibrin-based dermal matrices used as scaffolds in complete skin equivalents (including dermis and epidermis). The process involves synthesizing PdPFP-Jeff, a modified porphyrin incorporating palladium and Jeffamine ED 600, and covalently bonding it to alginate modified with
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