Evidence map›Paper›PMID 42222823›Full record

ArticleACS omega2026

Nectriatides with No Antifungal Activity Bind to Ergosterol and Potentiate the Antifungal Activity of Amphotericin B against

Keisuke Kobayashi, Ryosuke Miyake, Kenichiro Nagai, Yukino Sato, Reiko Seki, Kumiko Sakai-Kato, Shinichi Nishimura, Taichi Ohshiro, Hiroshi Tomoda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Raman Imaging of an Amphotericin B Potentiator in Single-CellThe journal of physical chemistry. B · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Keisuke KobayashiDepartment of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan.ORCID https://orcid.org/0000-0001-9580-2484
Ryosuke MiyakeDepartment of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan.ORCID https://orcid.org/0009-0007-5641-8712
Kenichiro NagaiMedicinal Research Laboratories, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan.
Yukino SatoDepartment of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan.
Reiko SekiMedicinal Research Laboratories, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan.
Kumiko Sakai-KatoLaboratory of Analytical Chemistry, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan.ORCID https://orcid.org/0000-0001-7068-7379
Shinichi NishimuraDepartment of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID https://orcid.org/0000-0002-5998-3780
Taichi OhshiroDepartment of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan.
Hiroshi TomodaDepartment of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan.ORCID https://orcid.org/0000-0002-1241-8901

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal cyclotetrapeptide nectriatide and its synthetic linear derivatives (nectriatide-based compounds, NCTs), having no antifungal activity, potentiated the antifungal activity of amphotericin B (AmB) against

Identifiers

PMID42222823
PMCPMC13216966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.