Evidence map›Paper›PMID 42222752›Full record

ArticleHRB open research2025

CP-EXCEL:  A feasibility randomised controlled trial of an online exercise programme for adults with cerebral palsy.

Manjula Manikandan, Pauline Hunter-Graham, Ailish McGahey, Miriam Creeger, Rebecca Walters, Aisling Walsh, Karen McConnell, Claire Kerr, Claire Kenny, Éabha Wall and 5 more

Abstract read
In one paragraph

Article in HRB open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Manjula ManikandanCP-Life Research Centre, School of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Dublin, Dublin 2, Ireland.ORCID https://orcid.org/0000-0003-2631-8482
Pauline Hunter-GrahamMae Murray Foundation, Northern Ireland, UK.
Ailish McGaheyCentral Remedial Clinic, Dublin, Ireland.
Miriam CreegerUP- The Adult Cerebral Palsy movement, London, UK.
Rebecca WaltersUniversity College London Hospitals NHS Foundation Trust, London, England, UK.
Aisling WalshDepartment of Public Health and Epidemiology, Royal College of Surgeons in Ireland, Dublin, Ireland.ORCID https://orcid.org/0000-0002-5312-5101
Karen McConnellSchool of Nursing and Midwifery, Queen's University Belfast, Belfast, UK.ORCID https://orcid.org/0000-0002-5221-9800
Claire KerrSchool of Nursing and Midwifery, Queen's University Belfast, Belfast, UK.ORCID https://orcid.org/0000-0003-2067-5091
Claire KennyPublic and Patient Involvement, contributor, Ireland.
Éabha WallPublic and Patient Involvement, contributor, Ireland.
Fiona WeldonPublic and Patient Involvement, contributor, Ireland.
Jessica BurkePublic and Patient Involvement, contributor, Ireland.
Kevin BravenderPublic and Patient Involvement, contributor, Ireland.
Rachel ByrneThe cerebral palsy foundation, New York, USA.
Jennifer RyanCP-Life Research Centre, School of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Dublin, Dublin 2, Ireland.ORCID https://orcid.org/0000-0003-3768-2132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Adults with cerebral palsy (CP) are at increased risk of non-communicable diseases and often experience secondary complications as they age. Physical activity can mitigate these risks and improve well-being. However, adults with CP face significant challenges in accessing structured, tailored exercise programmes due to limited service availability and environmental barriers. A group online exercise programme may overcome some of the barriers to accessing exercise faced by adults with CP. CP-EXCEL aims to evaluate the feasibility of an online exercise programme for adults with CP. The study will examine the demand, implementation, practicality, adaptability, acceptability, and potential efficacy of delivering the online exercise programme to adults with CP in Ireland. Methods: This feasibility randomised controlled trial will recruit 60 adults with CP. Participants will be randomly assigned to either an eight-week online exercise intervention or a control group. The feasibility of the programme will be evaluated across five key domains: 1) demand as indicated by recruitment rate; 2) implementation as indicated by attendance; 3) practicality as indicated by number and type of adverse events; 4) adaptability, by examining how the programme accommodates varying levels of mobility and associated impairments; and 5) acceptability explored through semi-structured interviews with participants. To assess preliminary efficacy, the Patient-Reported Outcomes Measurement Information System (PROMIS) will be used to measure changes in physical, mental, and social functioning at baseline and post-intervention. Quantitative outcomes will be analysed using linear mixed models, and qualitative data will be analysed using framework analysis. Conclusion: This study will provide valuable insights into the feasibility of an online exercise programme tailored for adults with CP And inform the design of a future fully powered randomised controlled trial.

Indexed as

AdultsCerebral palsyfitnessonline exercise programme

Identifiers

PMID42222752
PMCPMC13221627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.