ArticleChemical & biomedical imaging2026
Label-Free Detection of Acrosome Reaction of Human Sperm Based on Diffraction Phase Microscopy.
Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Label-free measurements of lipid droplets in cells based on quantitative differential phase contrast imaging with high oblique illumination.Biomedical optics express · 2026Article
- Fast full-color pathological imaging via an optimized illumination pattern with color transfer in Fourier ptychographic microscopy (OIP-CTFPM).Biomedical optics express · 2026Article
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12 authors.
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Abstract
The acrosome reaction (AR) is essential for successful fertilization, which is crucial for live sperm with fertilization potential in clinical practice. However, label-free assessment of the AR status of sperm is still challenging. In this study, a multimodal imaging system has been developed, integrating with fluorescence imaging, phase imaging, and bright-field imaging for observing the same sperm. The sperm phase characteristics were analyzed to assess the AR status. According to the phase in the acrosome and nucleus, the three-phase metrics (
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