ReviewChemical & biomedical imaging2026
Activatable NIR Schaap's 1,2-Dioxetane-Based Chemiluminescent Probes for Bioimaging Applications.
Review in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Dual-locked strategy for fluorescence/chemiluminescence dual-modal imaging reprogramming.Chemical science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Owing to the elimination of autofluorescence caused by real-time excitation with the external light source, chemiluminescent imaging possesses the advantages of improved signal-to-noise ratio and enhanced deep-tissue penetration. As an essential tool in optical imaging, near-infrared (NIR) chemiluminescent probes have attracted significant interest due to their superior tissue penetration depth and minimized light scattering. Molecular engineering that employs chemiluminescence resonance energy transfer (CRET) or extends conjugation of the original chemiluminescent (CL) molecule skeleton provides ways to extend CL emission into the NIR region. Compared with CL probes such as luminol or peroxyoxalates, Schaap's 1,2-dioxetane-based probes possess advantages of facile synthesis and modification and can be activated by diverse biomarkers, facilitating biological imaging. In this review, we begin with the molecular design strategies of NIR chemiluminescent probes, followed by their bioimaging applications for disease theranostics. Finally, existing challenges and future perspectives on NIR chemiluminescence imaging are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.