Evidence map›Paper›PMID 42222557›Full record

ReviewChemical & biomedical imaging2026

Perspective on Intraoperative Real-Time Biliary Tract Navigation: From Radiological to Fluorescent Imaging.

Chuxing Chai, Tze Cin Owyong, Yining Zhang, Siyang Ding, Pai Liu, Yuning Hong, Min Li

Abstract readReview
In one paragraph

Review in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chuxing ChaiDepartment of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Tze Cin OwyongDepartment of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
Yining ZhangTongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Siyang DingDepartment of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
Pai LiuCangzhou Institute of Tiangong University, Cangzhou 061000, China.ORCID https://orcid.org/0000-0002-9003-3652
Yuning HongDepartment of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.ORCID https://orcid.org/0000-0002-8085-1651
Min LiDepartment of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.ORCID https://orcid.org/0000-0002-0047-2804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate identification of biliary anatomy is essential in hepatobiliary surgery, as misinterpretation remains the leading cause of bile duct injuries, resulting in significant postoperative morbidity. Traditional approaches, including visual inspection, palpation, and intraoperative cholangiography, are constrained by anatomical variability, radiation exposure, procedural complexity, and workflow disruption. In this perspective, we highlight the clinical challenges of biliary navigation, review the emerging role of fluorescence-guided surgery using near-infrared indocyanine green for real-time, low-toxicity visualization, and discuss advances in next-generation fluorophores and imaging platforms. Our discussion aims to stimulate tool development to enhance intraoperative precision, reduce reliance on radiation, and improve patient safety in biliary surgery.

Indexed as

biliary tract imagingfluorescence cholangiographyfluorescence-guided surgeryindocyanine greenintraoperative cholangiographylaparoscopic cholecystectomynear-infrared imaging

Identifiers

PMID42222557
PMCPMC13217330

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.