Evidence map›Paper›PMID 42222429›Full record

ArticleArthroplasty today2026

Do Adductor Canal Blocks Provide Additional Analgesic Benefit to Periarticular Injection Alone for Primary Total Knee Arthroplasty?

Jonathan Brutti, Zachary Grand, Chukwuemeka U Osondu, Robert Birch, Charles M Lawrie

Abstract read
In one paragraph

Article in Arthroplasty today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathan BruttiFlorida International University Herbert Wertheim College of Medicine, Miami, FL, USA.
Zachary GrandFlorida International University Herbert Wertheim College of Medicine, Miami, FL, USA.
Chukwuemeka U OsonduBaptist Health Orthopedic Institute, Coral Gables, FL, USA.
Robert BirchOrthopaedic Institute of Henderson, Henderson, NV, USA.
Charles M LawrieBaptist Health Orthopedic Institute, Coral Gables, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The added benefit of preoperative, anesthesiologist-performed adductor canal blocks (ACBs) to a modern pain management regimen in total knee arthroplasty (TKA), including multimodal analgesia and periarticular injection (PAI), remains controversial. This study compared opioid consumption and postoperative pain in TKA patients receiving ACB + PAI vs PAI alone. Methods: This was a single-surgeon retrospective review of patients who underwent unilateral primary TKA over a 2-year period. During year 1, no patients received ACB. During year 2, all patients received ACB. Morphine milligram equivalents, visual analog scale (VAS), and summed pain intensity difference values were compared between both groups over the first 24 hours postoperatively. The final sample included 188 patients: 104 with ACB + PAI and 84 with PAI only. Results: The mean total morphine milligram equivalents of opioids administered was lower in the ACB + PAI group (31.6 [range: 0-177] vs 42.5 [range: 0-103.5]; Conclusions: The addition of an ACB to PAI was associated with lower postoperative pain values and reduced opioid consumption compared to PAI alone in the first 24 hours postoperatively.

Indexed as

Adductor canal blockOpioid consumptionPeriarticular injectionPostoperative pain managementTotal knee arthroplasty

Identifiers

PMID42222429
PMCPMC13217849

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.