Evidence map›Paper›PMID 42222287›Full record

ArticleFrontiers in physiology2026

Endonuclease G restores lipid homeostasis in spontaneously hypertensive rats: implications for mitochondrial function.

Petr Mlejnek, Miroslava Šimáková, Jan Šilhavý, František Liška, Tomáš Mráček, Josef Houštěk, Irena Marková, Martina Hüttl, Hana Malínská, Michal Pravenec

Abstract read
In one paragraph

Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Petr MlejnekInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Miroslava ŠimákováInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Jan ŠilhavýInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
František LiškaInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Tomáš MráčekInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Josef HouštěkInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Irena MarkováCenter for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czechia.
Martina HüttlCenter for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czechia.
Hana MalínskáCenter for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czechia.
Michal PravenecInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The mitochondrial endonuclease G ( Methods: To determine the metabolic consequences of Results: Conclusion: Restoration of

Indexed as

endonuclease G (Endog) geneinsulin resistancelipid and glucose metabolismspontaneously hypertensive rat (SHR)transgenic

Identifiers

PMID42222287
PMCPMC13215907

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.