Evidence map›Paper›PMID 42222286›Full record

SynthesisFrontiers in physiology2026

The effect of blood flow restriction training with different intermittent durations on the post-activation potentiation of lower limbs:a meta-analysis.

Xinrui Miao, Wenqing Chang, Yulin Yang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xinrui MiaoDepartment of Physical Education, Kunsan National University, Gunsan, Republic of Korea.
Wenqing ChangCollege of Physical Education, Putian University, Putian Fujian, China.
Yulin YangSchool of Sports, Northeast Electric Power University, Jilin, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This meta-analysis aimed to systematically evaluate the effect of blood flow restriction (BFR) training with different intermittent durations on the post-activation potentiation (PAP) of lower limbs, and clarify the optimal rest interval window and related key training parameters. Methods: Randomized controlled trials (RCTs) investigating the impact of BFR training on lower limb PAP were retrieved from PubMed, Web of Science, EBSCO, and CNKI databases in accordance with the PRISMA statement. The search period covered from the establishment of each database to November 15, 2025. The Cochrane Risk of Bias Tool was used for literature quality assessment, Review Manager 5.3 software for statistical analysis, Stata 17.0 software for sensitivity analysis, and Egger test combined with funnel plots for detecting publication bias. Results: A total of 16 RCTs involving 281 participants were included. The meta-analysis showed that lower limb BFR training significantly induced PAP compared with the control group [ Conclusion: Lower limb BFR training can effectively induce PAP. For BFR interventions targeting lower limb PAP induction, the optimal potentiation effect is achieved with squat exercises at an exercise intensity of 40%~70% 1RM, a compressive strength of 40%~60% absolute occlusion pressure (AOP), and an inter-set rest interval of 2~4 min. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42023478585.

Indexed as

back squatblood flow restriction trainingmeta-analysispost-activation potentiation enhancementrest interval

Identifiers

PMID42222286
PMCPMC13220168

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.