Pretreatment with different doses of oliceridine attenuates etomidate-induced myoclonus during painless gastroscopy: a randomized controlled trial.

Yingchuan Lin, Yun Dai, Weifeng Huang, Huaijian Zhang, Bin Yang

Abstract readClinical Trial

In one paragraph

Trial report in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Safety and Efficacy of Oliceridine Combined with Propofol for Painless Gastroscopy: A Single-Center, Randomized, Parallel Controlled Clinical Trial.Drug design, development and therapy · 2026
Trial

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingchuan Lin *Department of Anesthesiology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Yun Dai *Department of Endoscopy, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Weifeng Huang *Department of Gastroenterology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Huaijian ZhangDepartment of Anesthesiology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Bin YangDepartment of Anesthesiology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Etomidate is commonly used for sedation during gastroscopy but is associated with a high incidence of myoclonus. This study evaluated the effectiveness of oliceridine pretreatment in reducing etomidate-induced myoclonus. Methods: In this prospective, double-blind, randomized controlled trial, 150 patients undergoing painless gastroscopy were assigned to receive oliceridine at 0.01 mg/kg (Group A Results: The incidence of myoclonus was significantly lower in Groups A Conclusion: Pretreatment with oliceridine effectively reduces the incidence and severity of etomidate-induced myoclonus during painless gastroscopy without compromising hemodynamic stability. Clinical Trial Registration: http://www.chictr.org.cn, identifier ChiCTR2500103005.

Indexed as

etomidategastroscopymyoclonusoliceridinesedation

Identifiers

PMID42222170

DOI10.3389/fphar.2026.1664835

PMCPMC13215985

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.