Evidence map›Paper›PMID 42222103›Full record

ReviewFrontiers in cardiovascular medicine2026

Vascular age vs. chronological age in operative risk stratification.

Kenyon Sprankle, Christopher Potestio, Vonna Jonna Venkatasai S, Meghna Matthews, Lawrence J Mulligan

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kenyon SprankleCooper Medical School of Rowan University, Camden, NJ, United States.
Christopher PotestioCooper Medical School of Rowan University, Camden, NJ, United States.
Vonna Jonna Venkatasai SCooper Medical School of Rowan University, Camden, NJ, United States.
Meghna MatthewsCooper Medical School of Rowan University, Camden, NJ, United States.
Lawrence J MulliganCooper Medical School of Rowan University, Camden, NJ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early vascular aging (EVA) describes a disconnect between an individual's chronological age and their biological vascular age. It is thought to be caused by endothelial dysfunction, oxidative stresses, and chronic low-grade inflammation. Evidence collected over the past three decades suggests that vascular aging may be linked to and exacerbated by conditions such as hypertension (HTN), coronary artery disease (CAD) and heart failure with preserved ejection fraction (HFpEF). This accelerated vascular aging results in younger individuals having vascular profiles and perioperative risks that would be expected in individuals of a more advanced chronological age.

Indexed as

arterial stiffnesscoronary artery diseaseearly vascular agingheart failurehypertension

Identifiers

PMID42222103
PMCPMC13217578

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.