Evidence map›Paper›PMID 42221986›Full record

ReviewNeuro-oncology advances2026

Surgical techniques for patients with cancer-related neuropathic pain.

Erica Gillespie, Elise Bouchal, Gordon Li, Julie G Pilitsis

Abstract readReview
In one paragraph

Review in Neuro-oncology advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erica GillespieDepartment of Neurosurgery, University of Arizona College of Medicine, Tucson, AZ, USA.
Elise BouchalDepartment of Neurosurgery, University of Arizona College of Medicine, Tucson, AZ, USA.
Gordon LiDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Julie G PilitsisDepartment of Neurosurgery, University of Arizona College of Medicine, Tucson, AZ, USA.ORCID https://orcid.org/0000-0002-6488-9692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this manuscript, we discuss the use of neuromodulatory techniques such as intrathecal therapy (IT) and spinal cord stimulation (SCS) for cancer pain in neuro-oncology patients. Currently, cancer pain management relies on oral opioids, which have a number of systemic side effects particularly in a chronic setting. An escalation of pain therapy for pain relief, such as neuromodulation, is necessary to improve neuro-oncology patients' quality of life. The paper highlights the need for more comprehensive pain management for patients during and after receiving cancer therapies. IT allows analgesics to bypass the blood-brain barrier (BBB), generating rapid and effective analgesia with fewer side effects than oral drug administration. SCS can interrupt pain signals via electrical stimulation of the dorsal columns of the spinal cord. Here we present rationale and highlight individualized treatment options for these neuromodulatory techniques' use in a neuro-oncological setting.

Indexed as

cancer-related painintrathecal therapyneuromodulationneuro-oncologyspinal cord stimulation

Identifiers

PMID42221986
PMCPMC13221129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.