ArticleiScience2026
Equivalent low altitude building improves physiological adaptation at high altitude.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic high-altitude exposure contributes to hypoxia-related morbidity. We conducted a randomized crossover trial evaluating overnight exposure to an equivalent low altitude building (ELAB) for 12 weeks in acclimatized adults residing in Lhasa. ELAB significantly improved nocturnal oxygen saturation, reduced hypoxic burden, attenuated hemoglobin increases, and lowered selected blood pressure parameters, while cardiopulmonary exercise capacity remained stable. No serious adverse events occurred. These findings support a medical-engineering strategy to reduce physiological stress associated with chronic high-altitude exposure and provide controlled physiological evidence for a non-pharmacological intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.