Evidence map›Paper›PMID 42221804›Full record

ArticleAdvances in neurotoxicology2026

Selenoneine, a food chain component with potential neuroprotective effects against electrophilic mercury forms.

Guilherme S Rieder, Davide Zeppilli, Pablo A Nogara, Michael Aschner, Alexey A Tinkov, Isaac A Adedara, Diogo O G de Souza, Débora G de Souza, Laura Orian, Joao B T Rocha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in neurotoxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guilherme S RiederPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Davide ZeppilliDipartimento di Scienze Chimiche, Università degli Studi di Padova, Padova, Italy.
Pablo A NogaraInstituto Federal de Educação, Ciência e Tecnologia Sul-rio-grandense (IFSul), Bagé, Rio Grande do Sul, Brazil.
Michael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, United States.
Alexey A TinkovCenter of Bioelementology and Human Ecology, IM Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Isaac A AdedaraDepartamento de Bioquímica e Biologia Molecular, CCNE, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil.
Diogo O G de SouzaPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Débora G de SouzaPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Laura OrianDipartimento di Scienze Chimiche, Università degli Studi di Padova, Padova, Italy.
Joao B T RochaPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.

Funding

Mechanisms of Methylmercury Induced Neuron ToxicityR01ES007331 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 1996 to 2026
$10.6M
NIEHS NIH HHS R01 ES007331
6 · The paper itself

Abstract

Selenoneine, an antioxidant molecule analogous to ergothioneine, is not synthesized by vertebrates but can be acquired through the diet. Both selenoneine and ergothioneine contain redox-active groups: selone (-

Indexed as

ErgothioneineMercury emissionNeuroprotectionSeleniumSelenoneineSelenoneine diselenideToxicity

Identifiers

PMID42221804
PMCPMC13221188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.