Evidence map›Paper›PMID 42221792›Full record

ArticleFrontiers in nutrition2026

Joint association of estimated skeletal muscle mass index and prognostic nutritional index with all-cause mortality in individuals with non-metastatic nasopharyngeal cancer.

Fansu Huang, Cai Gong, Huan Luo, Qin Wang, Yanming Hu, Ruzhe Zhang, Yanni Hu, Tao Hou, Yangchun Xie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fansu HuangDepartment of Clinical Nutrition, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Cai GongDepartment of Clinical Nutrition, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Huan LuoDepartment of Radiology, Zhangjiajie People's Hospital, Zhangjiajie, Hunan, China.
Qin WangDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yanming HuDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ruzhe ZhangDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yanni HuDepartment of Clinical Nutrition, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Tao HouDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yangchun XieDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prognostic interplay between skeletal muscle mass and nutritional/immune status in non-metastatic nasopharyngeal carcinoma (NPC) is unclear. This study investigates the independent and joint association of estimated skeletal muscle mass index (eSMI) and Prognostic Nutritional Index (PNI) with all-cause mortality. Methods: We analyzed 942 non-metastatic NPC patients. Low muscle mass was defined by sex-specific 20th percentiles of eSMI. PNI was categorized using a clinical cutoff of 45. Patients were stratified into four groups: normal eSMI & high PNI (reference), normal eSMI & Low PNI, low eSMI & high PNI, and low eSMI & low PNI. Multivariate Cox models and a win ratio analysis were used to evaluate joint prognostic value. Results: During a median follow-up of 54 months, 204 deaths (21.7%) occurred. In multivariate Cox analysis, low PNI was independently associated with higher risk (HR = 1.68, Conclusion: Joint assessment of eSMI and PNI provides superior risk stratification. Pre-treatment assessment of these simple markers may facilitate targeted nutritional and supportive interventions.

Indexed as

all-cause mortalitycohortestimated skeletal muscle mass indexnasopharyngeal cancerprognostic nutritional index

Identifiers

PMID42221792
PMCPMC13215891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.