Evidence map›Paper›PMID 42221699›Full record

ArticleACS catalysis2025

Million-Fold Activation of C-H Bonds by Fluorinated Nonheme Fe

Bittu Chandra, Chupeng Li, Mursaleem Ansari, Jin Xiong, Alex Lovstedt, Yisong Guo, Marcel Swart, Lawrence Que

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS catalysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bittu ChandraDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0001-6071-8071
Chupeng LiDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Mursaleem AnsariInstitut de Química Computacional i Catàlisi and Department of Chemistry, University of Girona, 17003 Girona, Spain.
Jin XiongDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.ORCID 0000-0001-7443-0554
Alex LovstedtDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Yisong GuoDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.ORCID 0000-0002-4132-3565
Marcel SwartInstitut de Química Computacional i Catàlisi and Department of Chemistry, University of Girona, 17003 Girona, Spain.ORCID 0000-0002-8174-8488
Lawrence QueDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-0989-2813

Funding

Elucidate Mechanisms of Quinolone Alkaloid Biosynthesis via Iron(II)/2-Oxoglutarate Dependent Enzymes: Diverse, but Controlled ReactivityR01GM125924 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI Yisong Guo · 2018 to 2026
$3.3M
O-O Bond Activation (and Formation) at Bimetallic Enzyme Active SitesR35GM131721 · NIGMS · UNIVERSITY OF MINNESOTA · PI QUE, LAWRENCE · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM125924NIGMS NIH HHS R35 GM131721
6 · The paper itself

Abstract

Fe

Indexed as

C-H activationEpoxidationFluorinated cyclamNonheme oxygenase modelSecond sphere modification

Identifiers

PMID42221699
PMCPMC13221200

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.