ArticleFrontiers in chemistry2026
In search of the perfect
Article in Frontiers in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Upcycling Silicon as Heterogeneous Palladium Catalysts: Heck-Cassar Cross-Coupling in Batch and Flow Conditions.ChemSusChem · 2026Article
- In search of the perfectFrontiers in chemistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Developments in Suzuki-Miyaura (SM) couplings are discussed from a historical standpoint as they are especially valued C-C bond-forming reactions in the fine chemicals industry today. However, discussion from the increasingly important standpoint of sustainability is also considered when looking for conditions leading to the perfect coupling. Thus, several procedures now exist leading to the desired SM couplings, which reproducibly occur in or on water, rather than in traditional, petroleum-based organic solvents. Moreover, procedures based on low loadings of palladium catalysts are also in hand that ensure that this precious and, at one time, endangered metal will be available indefinitely. In addition, the beginning of a new series of ligands is discussed that, from a life cycle assessment perspective, meet the required criteria (including method of formation, avoidance of intellectual property (IP) issues, number of steps involved, cost, and effectiveness) and should, therefore, feature prominently in the development of SM couplings. This goal may even be more attainable considering the recently reported use of "on dirty water" conditions, which enables close-to-neat reactions to be combined with a highly concentrated "on water" effect.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.