Evidence map›Paper›PMID 42221530›Full record

ReviewChemical science2026

Fluorinated carbohydrate-based vaccines.

Elena Chikunova, James Suri, Kathrin Siebold, Ryan Gilmour

Abstract readReview
In one paragraph

Review in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elena ChikunovaInstitute for Organic Chemistry, University of Münster Corrensstraße 36 48149 Münster Germany ryan.gilmour@uni-muenster.de.ORCID https://orcid.org/0000-0002-6138-2036
James SuriInstitute for Organic Chemistry, University of Münster Corrensstraße 36 48149 Münster Germany ryan.gilmour@uni-muenster.de.ORCID https://orcid.org/0000-0002-2557-2115
Kathrin SieboldInstitute for Organic Chemistry, University of Münster Corrensstraße 36 48149 Münster Germany ryan.gilmour@uni-muenster.de.
Ryan GilmourInstitute for Organic Chemistry, University of Münster Corrensstraße 36 48149 Münster Germany ryan.gilmour@uni-muenster.de.ORCID https://orcid.org/0000-0002-3153-6065

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The structural virtuosity of carbohydrates forms the basis of a molecular recognition language that is ubiquitous in immunomodulatory processes. This diversity generates the complexity required to accommodate the bandwidth of information generated by immune interactions: it logically follows that this capacity underpins the evolutionary success of oligosaccharide permutations in this endeavour. Placing glycan function on a structural level is therefore a core research endeavour in understanding the non-covalent interactions that elicit an immune response and, by extension, leveraging these data to identify and validate new vaccine leads. Innovations to expedite the construction of well-defined, immuno-relevant carbohydrates has revolutionized the field, and focused attention on further structural refinements that are new to biology. Echoing the success of site-selective fluorination in pharmaceutical design, the precision introduction of C(sp

Identifiers

PMID42221530
PMCPMC13216891

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.