Evidence map›Paper›PMID 42221494›Full record

ArticleFrontiers in microbiology2026

Functional characterization of CreA, ZnT, and MTase as key regulators of cadmium resistance in

FangMei Wang, WenTao Zhong, Qiu Wang, Yue Xu, Hui Chen, ShuHao Wang, ChangZheng Fan, Zheng Li, BaiYu Li, XiaoFeng Li and 2 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

FangMei Wang *Hunan Provincial Institute of Product and Goods Quality Inspection, Changsha, China.
WenTao Zhong *Hunan Provincial Institute of Product and Goods Quality Inspection, Changsha, China.
Qiu Wang *Department of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, China.
Yue XuHunan Provincial Institute of Product and Goods Quality Inspection, Changsha, China.
Hui ChenHunan Provincial Institute of Product and Goods Quality Inspection, Changsha, China.
ShuHao WangHunan Provincial Institute of Product and Goods Quality Inspection, Changsha, China.
ChangZheng FanCollege of Environment Science and Engineering, Hunan Normal University, Changsha, China.
Zheng LiHunan Provincial Institute of Product and Goods Quality Inspection, Changsha, China.
BaiYu LiHunan Provincial Institute of Product and Goods Quality Inspection, Changsha, China.
XiaoFeng LiDepartment of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, China.
XiaoFeng DingKey Laboratory of Protein Chemistry and Development Biology of State Education Ministry of China, College of Life Science, Hunan Normal University, Changsha, China.
ShuangLin XiangKey Laboratory of Protein Chemistry and Development Biology of State Education Ministry of China, College of Life Science, Hunan Normal University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Following the implementation of the Heavy Metal Pollution Control Program in the Methods: Using high-throughput Illumina HiSeq sequencing, differentially expressed genes were identified, annotated, and classified through comprehensive bioinformatics analyses. The associated signaling pathways were systematically examined in detail for functional interpretation. Results: This study highlights novel Cd-resistant genes exhibiting pronounced differential expression, thereby offering valuable insights into the Cd-tolerance mechanisms of filamentous fungi under heavy metal stress. Discussion: These findings provide a solid foundation for improving fungal tolerance through targeted genetic modifications, such as small interfering RNA (siRNA) interference or gene overexpression, with potential applications in environmental bioremediation strategies.

Indexed as

cadmium (Cd) resistance mechanismsCREAheavy metal detoxification processesMTasePaecilomyces lilacinusZnT

Identifiers

PMID42221494
PMCPMC13218079

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.