ArticleJournal of surgical case reports2026
Adult ileocolic intussusception with lymphoma as the lead point: a case report.
Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Adult ileocolic intussusception is almost always associated with a pathological lead point. We present a 29-year-old male with autism spectrum disorder (ASD) who attended with a one-week history of colicky right iliac fossa pain and loose stools. Communication difficulties related to ASD delayed a clear clinical history. Abdominal ultrasonography demonstrated a 7.0 × 6.0 cm target sign in the subhepatic region. Contrast-enhanced computed tomography confirmed ileocolic intussusception extending to the hepatic flexure, with a heterogeneously enhancing 6.6 × 4 × 3.4 cm lead-point mass. Diagnostic laparoscopy was converted to open right hemicolectomy with ileocolic anastomosis. Histopathology revealed B-cell non-Hodgkin lymphoma, confirmed by immunohistochemistry (CD20+, BCL2+, BCL6+, MUM1+, and c-MYC+). The patient was referred for oncological management and was well at one-month review. This case highlights that adult intussusception caused by lymphoma can present insidiously, particularly in patients with impaired communication, and that early cross-sectional imaging and prompt surgical resection are essential.
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