Evidence map›Paper›PMID 42221430›Full record

ArticleInternational journal of women's health2026

Short-Term Success Rate and Risk Factors for Failure of the Urethral Plication Procedure in the Management of Post-Obstetric Fistula Closure Stress Urinary Incontinence Among Ugandan Women: A Prospective Cohort Study.

Musa Kayondo, Onesmus Byamukama, Brenda Ainomugisha, Rogers Kajabwangu, Paul Kato Kalyebara, Leevan Tibaijuka, Henry Mark Lugobe, Verena Alice Geissbuhler, Christopher Tarnay

Abstract read
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Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Musa KayondoDivision of Urogynecology and Female Pelvic Floor Medicine, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda.
Onesmus ByamukamaDivision of Urogynecology and Female Pelvic Floor Medicine, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda.ORCID 0009-0006-1910-9761
Brenda AinomugishaDivision of Urogynecology and Female Pelvic Floor Medicine, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda.ORCID 0009-0001-8150-1645
Rogers KajabwanguDivision of Urogynecology and Female Pelvic Floor Medicine, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda.ORCID 0000-0003-4101-011X
Paul Kato KalyebaraDivision of Urogynecology and Female Pelvic Floor Medicine, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda.
Leevan TibaijukaDivision of Urogynecology and Female Pelvic Floor Medicine, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda.ORCID 0000-0002-2572-4051
Henry Mark LugobeDivision of Urogynecology and Female Pelvic Floor Medicine, Mbarara University of Science and Technology, Faculty of Medicine, Mbarara, Uganda.ORCID 0000-0001-8177-8786
Verena Alice GeissbuhlerDepartment of Gynecology, University Hospital Basel, Basel, Switzerland.ORCID 0000-0001-8678-4923
Christopher TarnayDepartment of Obstetrics and Gynecology, David Geffen School of Medicine University of California, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine the six-month success rate and risk factors for failure of the urethral plication procedure in the management of post-obstetric fistula closure Stress Urinary Incontinence (SUI). Methods: This was a prospective cohort study of 70 women with moderate or severe SUI who underwent surgery for post-obstetric fistula closure SUI using the urethral plication procedure, managed at eight fistula repair sites in Uganda. Participants underwent clinical evaluation, methylene blue dye testing, post-void residual assessment, and single-channel cystometry to confirm stress urinary incontinence and exclude residual fistula, overflow incontinence, and urge incontinence. Urethral plication was the primary continence procedure; however, in some participants, concomitant reconstructive procedures, including urethral elongation and urethral reconstruction were performed based on intraoperative anatomical findings. The participants were followed up for a period of six months. Assessment for statistically significant changes in the grade of SUI at baseline and at six months post-surgery among the failures was done using Bowker's test of symmetry and the Stuart-Maxwell test for marginal homogeneity. Descriptive analyses and multivariable log binomial regression were performed to determine risk factors for failure. Results: A total of 70 women were enrolled with a mean age of 34 (SD ±12.1) years. Concomitant reconstructive procedures were performed in 26/70 (37%) of participants. The success rate at six months post-surgery was 61% (43/70) dropping from 70% (49/70) at time of discharge. Of the 27 participants who remained incontinent, 15 (56%) demonstrated improvement in the grade of incontinence (Bowker's test; χ Conclusion: The short-term success rate of the urethral plication procedure is moderately high, and in carefully selected women, it appears to be a safe and effective option for managing post-obstetric fistula closure stress urinary incontinence. Although the procedure is more likely to fail in women with severe vaginal scarring, the severity of the incontinence improves in those that fail.

Indexed as

post-obstetric fistula closure stress urinary incontinencesuccess rateurethral plication

Identifiers

PMID42221430
PMCPMC13220834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.