Evidence map›Paper›PMID 42221287›Full record

ArticlePlastic and reconstructive surgery. Global open2026

From Liability to Viability: Salvage of a Lower-limb Shearing Injury Using a "Spare-part" Graft from Chemically Compromised Skin.

Henok T Debela, Sakar Gupta, Fatima Z Khan, Matteo Laspro, Noelle T Thompson, Michael L Bentz

Abstract readCase Reports
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Henok T DebelaFrom the Division of Plastic and Reconstructive Surgery, Department of Surgery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Sakar GuptaDivision of Plastic and Reconstructive Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Fatima Z KhanDepartment of Surgery, University of Toledo, College of Medicine and Life Sciences, Toledo, OH.
Matteo LasproDivision of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine of USC, Los Angeles, CA.
Noelle T ThompsonDepartment of Surgery, University of Toledo, College of Medicine and Life Sciences, Toledo, OH.
Michael L BentzDivision of Plastic and Reconstructive Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shearing injuries are complex traumatic wounds that present major reconstructive challenges. These are particularly difficult in low-resource settings where access to microsurgical techniques, negative pressure therapy, or skin substitutes is limited. These challenges are compounded when the avulsed skin has been chronically exposed to unregulated skin-lightening agents. Products containing hydroquinone, corticosteroids, or mercury compromise skin integrity and healing capacity. This case report presents a novel application of chemically compromised, avulsed skin as a full-thickness skin graft (FTSG) in a 30-year-old Somali woman following a road traffic accident. The patient sustained a large noncircumferential shearing injury of the right leg. On examination, the avulsed skin appeared thin, hypopigmented, and atrophic. This is consistent with chronic skin bleaching. In the absence of systemic injuries, the surgical team opted to salvage the avulsed tissue. After thorough debridement and irrigation of the wound bed, the compromised skin was immediately defatted, meshed, and reapplied as a full-thickness skin graft. We secured the graft with staples and a bolster dressing. The limb was immobilized. On the first, second, and tenth-week follow-ups, the graft demonstrated good take, progressive epithelialization and stable pigmentation. There were no signs of infection, graft loss, or contracture. This case illustrates the potential utility of chemically altered, avulsed skin as an autologous graft source. It underscores the importance of surgical adaptability, careful preoperative and intraoperative assessment, and pragmatic innovation in trauma care under challenging clinical settings. Further studies are needed to define criteria for safe use of chemically compromised skin in reconstructive surgery.

Identifiers

PMID42221287
PMCPMC13218668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.