Evidence map›Paper›PMID 42221206›Full record

ReviewOrthopaedic journal of sports medicine2026

Outcomes of Restorative Treatment for Isolated Patellar Cartilage Lesions: A Systematic Review and Meta-analysis.

Jelle P van der List, Tarik Taoufik, David C Flanigan, Robert A Magnussen, Nicholas A Apseloff

Abstract readReview
In one paragraph

Review in Orthopaedic journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jelle P van der ListDepartment of Orthopaedic Surgery and Sports Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-7940-5152
Tarik TaoufikDepartment of Orthopaedic Surgery and Sports Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
David C FlaniganDepartment of Orthopaedic Surgery and Sports Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-8876-7043
Robert A MagnussenDepartment of Orthopaedic Surgery and Sports Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-9864-1508
Nicholas A ApseloffDepartment of Orthopaedic Surgery and Sports Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patellar cartilage lesions often cause debilitating symptoms, and several treatments exist. However, most review studies have combined patellar and trochlear lesions. Purpose: To assess the outcomes of different treatments of only patellar cartilage lesions. Study Design: Systematic review; Level of evidence, 4. Methods: The PubMed, Embase, and Cochrane Library databases were searched in March 2025 for clinical studies reporting outcomes of advanced cartilage treatments beyond microfracture or chondroplasty. The inclusion criteria consisted of isolated patellar lesions (no trochlear or bipolar lesions), regardless of concomitant procedures, with a minimum 1-year follow-up and at least 10 patients. Relevant outcomes were failure, reoperation, and complication rates, and patient-reported outcome measures (PROMs). Random-effect models were used, and outcomes were reported with 95% CIs. Results: A total of 36 studies (1058 patients; mean age, 32 years; follow-up, 5.1 years) were included. Most patients underwent (matrix-induced) autologous chondrocyte implantation (MACI/ACI; mean lesion, 4.3 cm Conclusion: In this systematic review with meta-analysis, overall good to excellent outcomes were observed for all identified treatments, with mean estimated failure rates <10% and PROMs ranging from 70% to 85% of the maximum score. Treatment with OAT/mosaicplasty and AMIC resulted in the highest IKDC score for patients with lesions <3.5 cm

Indexed as

autologous chondrocyte implantationcartilage lesionosteochondral allograftosteochondral autograft transferpatellatibial tubercle osteotomy

Identifiers

PMID42221206
PMCPMC13219958

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.