Evidence map›Paper›PMID 42221003›Full record

ArticleFrontiers in pediatrics2026

The dose-response relationship between physical activity and school scoliosis screening positive in children and adolescents: a preliminary cross-sectional study.

Chen Chen, Yang Yang, Zhen Chen, Lingyan Yuan

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Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Chen Chen *School of Physical Education, Sports Kinesiology, Shanghai Normal University, Shanghai, China.
Yang Yang *School of Physical Education, Sports Kinesiology, Shanghai Normal University, Shanghai, China.
Zhen ChenDepartment of Rehabilitation Medicine, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lingyan YuanSchool of Physical Education, Sports Kinesiology, Shanghai Normal University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While physical inactivity is an established risk factor for adolescent idiopathic scoliosis (AIS), dose-response relationships for physical activity (PA) parameters remain unquantified. This study examined associations between PA dose (amount, duration, frequency, type) and scoliosis screening positive (SSP), exploring optimal thresholds. Methods: In this cross-sectional analysis, 1,051 students (mean age 10.69 ± 2.45 years) from 8 Shanghai schools underwent scoliometer screening (ATR ≥5° defined as SSP). PA was assessed via validated The Physical Activity Questionnaire for Older Children(PAQ-C) questionnaire[scores≤2: light PA(LPA), scores2-3: moderate PA(MPA), scores > 3: vigorous PA(VPA)]. Logistic regression modeled scoliosis risk across PA strata. Restricted cubic splines (RCS) characterized dose-response curves. Subgroup analyses explored age-specific effects. Results: In two multivariable-adjusted models, both LPA and VPA demonstrated significantly elevated risks for SSP compared to MPA (adjusted OR = 3.30, 95% CI 1.92-5.68 and OR = 3.65, 95% CI 2.14-6.24, respectively), revealing a U-shaped dose-response relationship with risk nadir at PAQ-C scores≈2.7(p < 0.05). Exercise frequency <3 sessions/week (OR = 4.68, 95% CI 2.75-7.98), session duration <∼54 min or >90 min (OR = 3.43 and 2.75), and cumulative participation >2 years (OR = 3.37, 95% CI 1.89-6.01) were positively associated with SSP ( Conclusions: The amount of physical activity in children and adolescents shows a U-shaped association with SSP, with moderate PA (approximately 54 min/day, 3-4 days/week) being associated with the lowest SSP odds, while low and vigorous PA are associated with higher odds. Participation in water sports and team sports is inversely associated with SSP.These findings highlight potential associations that warrant further longitudinal investigation.

Indexed as

adolescentschildrendose-response relationshipphysical activityscoliosis screening positive

Identifiers

PMID42221003
PMCPMC13216475

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.