ArticleFrontiers in pediatrics2026
Analysis of the epidemic situation of respiratory pathogens in central and southern China before and after the COVID-19 pandemic.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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7 authors.
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Abstract
Background: Respiratory tract infection is a common disease leading to pediatric hospitalization, exhibiting different epidemiological trends with seasons and ages. This study retrospectively analyzed the infection status of 12 respiratory pathogens from 2018 to 2023, and examined the changes before and after the COVID-19 pandemic. Methods: A total of 51,597 hospitalized children with suspected respiratory tract infection, who underwent multiplex PCR testing in a tertiary hospital in Changsha from 2018 to 2023 were included. Testing items included respiratory syncytial virus, adenovirus, influenza virus, parainfluenza virus, Mycoplasma pneumoniae, Chlamydia pneumoniae, and bacterial culture results, among others. Results: The infant group had the highest positive rate at 39.25% (7,729/19,693), and the school-age group the lowest at 25.34% (2,015/7,951) ( Conclusion: Due to the impact of the epidemic, the positive rate and disease spectrum of respiratory pathogens have changed. The pandemic induced an initial suppression followed by a marked resurgence of RSV, influenza, and M. pneumoniae after restrictions were lifted. Segmented regression confirmed RSV exhibited the steepest post-pandemic rebound, and toddlers born during lockdown showed a disproportionate surge in infections, supporting the "immunity debt" hypothesis. These findings underscore the importance of age-specific surveillance for preventing pediatric critical illness.
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