ArticleFrontiers in pediatrics2026
Age-related changes in lens thickness in children aged 3-17 years and its association with myopia and ocular biological parameters: a cross-sectional and longitudinal study.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate age-related changes in lens thickness(LT)and its associations with ocular biometrics and refractive status in children aged 3-17 years. Methods: A retrospective analysis of 699 children (1,398 eyes) undergoing ophthalmic examinations (June-August 2023).LT,axial length (AL), anterior chamber depth (ACD), mean corneal curvature (Km), and central corneal thickness (CCT) were measured via IOL Master 700. Longitudinal data were collected at 1-year ( Results: The median of LT was 3.42 mm (25th percentile, P25: 3.28; 75th percentile, P75: 3.56), which was significantly negatively correlated with age (r = -0.434, Conclusion: LT follows an age-dependent pattern of early decline, adolescent stabilization, and subsequent thickening. Thicker lenses in non-myopic children suggest lenticular compensation in refractive development. Age 10 represents a critical intervention window, with LT serving as a potential biomarker for pediatric refractive status assessment.
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