ArticleWorld journal of clinical pediatrics2026
Pediatric acute cholecystitis: Risk factors and outcomes.
Article in World journal of clinical pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPediatric acute cholecystitis is a growing concern due to rising childhood obesity rates and associated metabolic abnormalities.
aimTo identify demographic and clinical risk factors, evaluate surgical outcomes, and analyze the impact of complications on hospitalization in pediatric patients undergoing cholecystectomy.
methodsA retrospective study was conducted on 12750 pediatric patients who underwent cholecystectomies in 2022. Data were collected from a de-identified National Surgical Quality Improvement Program database, including age, gender, race, body mass index (BMI) status, clinical presentation, complications, and treatment details. Risk factors were assessed using logistic regression, and Kaplan-Meier analysis was used to evaluate postoperative readmission rates. Descriptive statistics explored demographic patterns and surgical outcomes.
resultsOut of 12750 pediatric patients, the mean age was 12.8 years, with a median of 13.0 years. Gender distribution included 74.8% females and 25.2% males. Obesity (BMI ≥ 30 kg/m
conclusionPediatric acute cholecystitis is an emerging public health concern linked to rising obesity rates. Early surgical intervention minimizes complications and reduces hospitalization durations. Pediatric-specific adaptations in the Tokyo Guidelines 2018 may be necessary to account for age-related differences in clinical presentation and facilitate accurate diagnosis. Addressing racial disparities and targeted prevention strategies is critical for optimizing outcomes.
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