Evidence map›Paper›PMID 42220947›Full record

ArticleWorld journal of clinical pediatrics2026

Distinct early gut microbiota patterns by delivery mode within 100 hours of birth.

Palittiya Sintusek, Pavit Klomkliew, Suthida Visedthorn, Kittima Phutthawong, Tanawan Noicharoen, Areewan Soontornsook, Duc Long Tran, Sunchai Payungporn

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Palittiya SintusekCenter of Excellence in Thai Pediatric Gastroenterology, Hepatology and Immunology, Division of Gastroenterology, Department of Pediatrics, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. palittiya.s@chula.ac.th.
Pavit KlomkliewCenter of Excellence in Systems Microbiology, Department of Biochemistry, Chulalongkorn University, Bangkok 10330, Thailand.
Suthida VisedthornCenter of Excellence in Systems Microbiology, Department of Biochemistry, Chulalongkorn University, Bangkok 10330, Thailand.
Kittima PhutthawongCenter of Excellence in Systems Microbiology, Department of Biochemistry, Chulalongkorn University, Bangkok 10330, Thailand.
Tanawan NoicharoenDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Areewan SoontornsookDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Duc Long TranCenter of Excellence in Thai Pediatric Gastroenterology, Hepatology and Immunology, Division of Gastroenterology, Department of Pediatrics, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Sunchai PayungpornCenter of Excellence in Systems Microbiology, Department of Biochemistry, Chulalongkorn University, Bangkok 10330, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDisruptions in the early-life gut microbiome have been reported to be associated with various health conditions. However, few studies have investigated the establishment of the gut microbiota in the immediate postnatal period.

aimTo characterize the gut microbiota of neonates within the first 100 hours after birth.

methodsA total of 512 healthy neonates born at a tertiary hospital were enrolled in this study. Stool samples were collected between March 2024 and December 2024 and categorized by delivery mode and stool collection time. Microbiota diversity and composition were assessed using full-length 16S rDNA sequencing. Stool samples from 140 neonates with predominant breastfeeding were analyzed.

resultsOf the 140 neonates, 70 (50%) were female, 66 (47.1%) were delivered by vaginal delivery (VD), 74 (52.9%) were delivered by cesarean section (CS), and 87 (62.1%) were firstborn. The time of stool collection ranged from 13.2 minutes to 109.82 hours. A significant difference in the time of stool collection was observed between CS and VD neonates (43.0 hours; 95%CI: 35.8-50.1

conclusionDespite predominant breastfeeding, CS neonates showed reduced colonization by

Indexed as

Cesarean sectionEarly lifeFeedingGut microbiotaNeonateNormal labor

Identifiers

PMID42220947
PMCPMC13217197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.