Evidence map›Paper›PMID 42220946›Full record

ArticleWorld journal of clinical pediatrics2026

Study of the gut microbiome profile in full-term infants with necrotizing enterocolits.

Eman Hamza Hassan, Wessam Zaghloul, Shwikar Mahmoud Ahmed, Ahmed M Ghozi, Ibrahim A Abdelwahab

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eman Hamza HassanDepartment of Pediatrics, Faculty of Medicine Alexandria University, Alexandria 21526, Egypt.
Wessam ZaghloulDepartment of Pediatrics, Faculty of Medicine Alexandria University, Alexandria 21526, Egypt. wessam.ahmed@alexmed.edu.eg.
Shwikar Mahmoud AhmedDepartment of Medical Microbiology and Immunology, Faculty of Medicine Alexandria University, Alexandria 21526, Egypt.
Ahmed M GhoziDepartment of Clinical Pharmacy, Pediatric Surgery and Internal Medicine Units, Alexandria 21526, Egypt.
Ibrahim A AbdelwahabDepartment of Microbiology and Immunology, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria 21648, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNecrotizing enterocolitis (NEC) is a severe gastrointestinal disease that primarily affects preterm. Recently, cases with similar clinical manifestations have been observed in full-term infants without Hirschsprung's disease. Dysbiosis suggested to have role in development of NEC.

aimTo compare the gut microbiome composition between full term infants with NEC and healthy controls and to evaluate the impact of feeding sources on microbial diversity.

methodsTen full term infants with NEC and six matched healthy breastfed control infants were enrolled in the study. Triplicate stool samples were collected from the enrolled infants. Genomic DNA was isolated and subjected to polymerase chain reaction analysis.

results

conclusionFull-term Egyptian infants with NEC exhibit reduced microbial diversity and alterations in bacterial abundance, supporting a potential link between dysbiosis and NEC. Feeding practices, particularly breastfeeding, appear to influence the gut microbiome profile regardless of NEC status. Although

Indexed as

BifidobacteriaDysbiosisFull-term infantsGut microbiomeNecrotizing enterocolitis

Identifiers

PMID42220946
PMCPMC13217207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.