Evidence map›Paper›PMID 42220935›Full record

ReviewWorld journal of clinical pediatrics2026

Neuro-ophthalmic review on pediatric myopia: Advancing from refraction to a brain-centric model of axial growth.

Matteo Capobianco, Simonetta Gaia Nicolosi, Edoardo Dammino, Francesco Cappellani, Marieme Khouyyi, Fabiana D'Esposito, Caterina Gagliano, Marco Zeppieri

Abstract readReview
In one paragraph

Review in World journal of clinical pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matteo CapobiancoEye Clinic, Policlinico G. Rodolico, University of Catania, Catania 95121, Italy.
Simonetta Gaia NicolosiFaculty of Medicine, University of Catania, Catania 95123, Italy.
Edoardo DamminoFaculty of Medicine, University of Catania, Catania 95123, Italy.
Francesco CappellaniDepartment of Medicine and Surgery, University of Enna "Kore", Enna 94100, Italy.
Marieme KhouyyiDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina 98121, Italy.
Fabiana D'EspositoDepartment of Medicine and Surgery, University of Enna "Kore", Enna 94100, Italy.
Caterina GaglianoDepartment of Medicine and Surgery, University of Enna "Kore", Enna 94100, Italy.
Marco ZeppieriDepartment of Ophthalmology, University Hospital of Udine, Udine 33100, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric myopia is conventionally characterized as a refractive anomaly influenced by optical defocus and environmental factors. Emerging evidence suggests that axial elongation during childhood may be usefully reframed through a neuro-ophthalmic perspective, integrating retinal signaling, visual cortex maturation, and neuroplasticity. This minireview examines myopia within an eye-brain axis framework, emphasizing the roles of retinal neurotransmitters, dopaminergic pathways, and visual processing networks in regulating eye growth. Here, "brain-centric" denotes a clinically integrative model in which neurodevelopmental state and brain-governed behaviors (

Indexed as

Axial lengthChildDopamineEyeMyopiaNeuroplasticityRetinaVisual pathways

Identifiers

PMID42220935
PMCPMC13217051

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.