Evidence map›Paper›PMID 42220862›Full record

ArticleCureus2026

Low-Dose Radiation for Knee Osteoarthritis: A Case Report.

Molly R Manning, Thomas R Eanelli

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Molly R ManningRadiation Oncology, Touro College of Osteopathic Medicine, Middletown, USA.
Thomas R EanelliRadiation Oncology, Garnet Health, Middletown, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional osteoarthritis (OA) treatment focuses on symptom management, including nonsteroidal anti-inflammatory drugs (NSAIDs), duloxetine, intra-articular glucocorticoids, or surgical intervention. Unfortunately, these approaches may provide inadequate symptom relief or can be contraindicated in patients with comorbidities such as cardiac issues, diabetes, and liver dysfunction. This underscores the necessity for alternative management options for OA. Low-dose radiation therapy (LDRT), widely used in European countries for the management of painful musculoskeletal conditions, has emerged as a promising option for pain relief in OA. We present the case of a 72-year-old man with a history of seven meniscectomies and bilateral knee OA. Due to minimal pain relief from prior treatments, the patient received 50 cGy per fraction (total of 3 Gy/6 fractions) to each knee three times per week for two weeks. After the completion of this treatment, the patient experienced substantial pain relief, meeting the Osteoarthritis Research Society International (OARSI) responder criteria. This case aims to discuss the need to optimize OA management by establishing collaborative, multidisciplinary clinics within hospitals.

Indexed as

arthritis cliniccomplementary and alternative therapyknee osteoarthritislow-dose radiation therapymultidisciplinary approach

Identifiers

PMID42220862
PMCPMC13220658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.