Evidence map›Paper›PMID 42220820›Full record

ArticleCureus2026

Genetic Analysis of Patients With Common Variable Immunodeficiency Followed in the Pulmonology Department: A Report of Five Patients.

Loubna Boumekrat, Abir Bouhamdi, Badereddine Elmakhzan, Souad Aalil, Btissame Es-Sabbahi, Lamiae Senhaji, Meryem Karhate, Mounia Serraj, Mohamed ElBiaze, Mohamed Chakib Benjelloun and 1 more

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In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Loubna BoumekratPneumology, Hassan II University Hospital, Fez, MAR.
Abir BouhamdiPneumology, Hassan II University Hospital, Sidi Mohamed Ben Abdellah University, Fez, MAR.
Badereddine ElmakhzanMedical Genetics, Faculty of Medicine and Pharmacy, Hassan II University Hospital, Fez, MAR.
Souad AalilPneumology, Hassan II University Hospital, Fez, MAR.
Btissame Es-SabbahiPulmonology and Critical Care, Hassan II University Hospital, Fez, MAR.
Lamiae SenhajiPneumology, Hassan II University Hospital, Fez, MAR.
Meryem KarhatePneumology, Hassan II University Hospital, Fez, MAR.
Mounia SerrajPneumology, Hassan II University Hospital, Fez, MAR.
Mohamed ElBiazePneumology, Hassan II University Hospital, Fez, MAR.
Mohamed Chakib BenjellounPneumology, Hassan II University Hospital, Fez, MAR.
Bouchra AmaraPneumology, Hassan II University Hospital, Fez, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by hypogammaglobulinemia, impaired vaccine response, and increased susceptibility to infections. Advances in molecular genetics have enabled the identification of monogenic forms in an increasing proportion of patients. In this study, a targeted genetic panel based on the 2022 International Union of Immunological Societies classification was performed in five patients presenting with a phenotype compatible with CVID. A genetic abnormality was identified in two (40%) patients, including a variant in the

Indexed as

cd3gcommon variable immunodeficiency (cvid)geneticsil7rnfkb1primary immunodeficiency

Identifiers

PMID42220820
PMCPMC13218395

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.