ArticleCureus2026
Leukocytosis in Diabetic Ketoacidosis Without Infection: A Diagnostic Challenge.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetic ketoacidosis (DKA) is a potentially life-threatening condition that requires prompt and precise management. While concurrent infection is a common precipitating factor, an elevated white blood cell (WBC) count does not necessarily indicate active infection. This case report illustrates a patient presenting with DKA and a high WBC count, but not showing any signs of infection. WBC level normalised after treatment of DKA, without the use of antibiotics. C-reactive protein and procalcitonin levels aided decision-making. Further studies are needed to validate the diagnostic value of these biomarkers and potentially establish a reliable tool to guide antibiotic stewardship. Reducing unnecessary antibiotic use in this context may significantly lower hospital costs and mitigate the growing threat of antimicrobial resistance. Optimising infection assessment in DKA patients remains an important clinical and research priority.
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Registered trials
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