ArticleCureus2026
Multifocal Septic Manifestations of Chronic Krokodil Abuse.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case report highlights the severe clinical course of a 30-year-old woman with a history of intravenous drug abuse, who presented to the emergency department with debilitating lower back pain. Initial evaluations revealed a critical condition, with septic emboli disseminated throughout her lungs, brain, and kidneys, likely secondary to her intravenous drug use. Further investigation suggested the involvement of krokodil (desomorphine), a potent and highly corrosive opioid, which has recently resurfaced in rural American communities due to its low cost and availability compared to fentanyl and xylazine. Krokodil, produced from codeine and toxic chemicals, causes extreme tissue damage, including ulcerations and gangrene. Radiological studies confirmed septic thrombosis, multiple septic emboli, and bilateral acute pyelonephritis, prompting immediate broad-spectrum antibiotic treatment. Despite initial stabilization, the patient's condition escalated, necessitating a laminectomy for epidural abscess evacuation. Her treatment was complicated by withdrawal symptoms, and further bacterial cultures identified
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