Evidence map›Paper›PMID 42220755›Full record

ArticleCureus2026

Management of a Complex Case of Gingival Enlargement Associated With Underlying Arteriovenous Malformation: A Five-Year Follow-Up Case Report.

Nefeli Christou, Ioannis Michalis, Ioanna Mitsika, Spyridon Silvestros, Evangelia Zampa

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nefeli ChristouDentistry, National and Kapodistrian University of Athens, Athens, GRC.
Ioannis MichalisDentistry, National and Kapodistrian University of Athens, Athens, GRC.
Ioanna MitsikaDentistry, National and Kapodistrian University of Athens, Athens, GRC.
Spyridon SilvestrosDentistry, National and Kapodistrian University of Athens, Athens, GRC.
Evangelia ZampaDentistry, National and Kapodistrian University of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arteriovenous malformations (AVMs) are high-flow congenital vascular anomalies characterized by abnormal direct communication between arteries and veins, bypassing the capillary bed. Gingival enlargement or gingival overgrowth is a common gingival disease characterized by an increase in the size of the gingival tissues. The main factors of gingival enlargement are inflammation, drugs, systemic conditions or diseases, neoplastic or false enlargements, and local factors, such as plaque, calculus, and/or overhanging restorations. The purpose of this article is to present an interesting case of the management of a patient with mandibular gingival enlargement occurring in association with an underlying AVM.  A 24-year-old non-smoker female patient presented to the periodontal clinic for the evaluation of a gingival overgrowth on the right side of the mandible that had developed over a four-week period, following a referral from her vascular specialist. Patient was previously diagnosed with an intraosseous AVMs in jaws (j-AVMs). Her medical history consisted of undergone embolization therapy for the j-AVM one year before. Clinical evaluation revealed an asymptomatic, soft-consistency, red/purple tumor-like mass with a broad base, measuring 0.5 x 0.5 cm. The surrounding gingival tissues in the right mandibular region appeared hyperplastic and edematous. A diagnosis of generalized gingivitis was established. The region of AVM was topographically associated with the vascular lesion of the mandibular gingiva. The gingival hyperplasia was distinguished from the underlying AVM, clarifying that the two represented coexisting independent lesions. The coexistence of gingival overgrowth with an underlying intraosseous AVM is exceptionally uncommon and presents notable challenges in clinical management and treatment. This case highlights the importance of adopting a conservative and multidisciplinary management approach, particularly in patients with high-flow vascular anomalies, where invasive procedures may pose substantial risks. Effective management relies on close collaboration among dental clinicians, radiologists, and vascular specialists.

Indexed as

arteriovenous malformationgingival enlargementhigh-flow vascular anomaliesintraosseous arteriovenous malformationvascular lesions

Identifiers

PMID42220755
PMCPMC13215782

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