Evidence map›Paper›PMID 42220681›Full record

ReviewCureus2026

Pediatric Congenital Tracheobronchial Variants and Their Clinical Significance for Endotracheal Intubation and Airway Management: A Scoping Review of Fetal, Neonatal, and Pediatric Cases.

Spyridon Kanakaris, Theano Demesticha, Dimitrios Filippou, George Triantafyllou, George Tsakotos, Nikolaos Lazaridis, Maria Piagkou

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Spyridon KanakarisDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, GRC.
Theano DemestichaDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, GRC.
Dimitrios FilippouDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, GRC.
George TriantafyllouDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, GRC.
George TsakotosDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, GRC.
Nikolaos LazaridisDepartment of Anatomy and Surgical Anatomy, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Maria PiagkouDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital tracheobronchial variants (CTBVs) may distort airway landmarks, alter carinal recognition, and complicate ventilation during pediatric endotracheal intubation. Although uncommon, these anomalies can create important peri-intubation risks that are often underrecognized. This scoping review was conducted in accordance with the Joanna Briggs Institute methodology and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidance. Using a Population-Concept-Context framework, we identified human case reports and small case series describing congenital tracheal or bronchial anomalies relevant to intubation, bronchoscopy, ventilation, or airway planning. Searches were performed in PubMed, Scopus, and Web of Science, with additional studies identified through manual searching. Sixty-six records were identified. After removal of one duplicate, 61 records from the database search were screened, 42 were excluded, and 23 full-text reports were assessed. Twenty studies were included, comprising 18 case reports and two small case series. Six studies described tracheal agenesis or atresia, four bronchial atresia, three tracheal bronchi, three bridge bronchi with or without pulmonary artery sling, and four bronchial isomerism or laterality defects. Cases ranged from 21 weeks of gestation to 15 years of age. Tracheal agenesis or atresia produced the most severe cannot-intubate presentations. Fixed stenotic lesions increased risks during tube passage and sizing, whereas distal anomalies more commonly mimicked selective intubation, mucus plugging, or refractory wheeze. CTBVs have important implications for pediatric airway management. Pre-intubation anatomical assessment and early bronchoscopic confirmation may reduce avoidable complications and support safer individualized airway planning.

Indexed as

bridge bronchusbronchial atresiabronchial isomerismbronchoscopyendotracheal intubationpediatric airwaypulmonary artery slingscoping reviewtracheal agenesistracheal bronchus

Identifiers

PMID42220681
PMCPMC13221611

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.