Evidence map›Paper›PMID 42220638›Full record

ArticleJAACAP open2026

Continuous Versus Grouping Approaches to Resilience: Predicting Mental Health Following Adversity in Two Longitudinal Datasets.

Lauren R Borchers, Chase Antonacci, William E Copeland, Michael J Meaney, Ian H Gotlib

Abstract read
In one paragraph

Article in JAACAP open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lauren R BorchersStanford University, Stanford, California.
Chase AntonacciStanford University, Stanford, California.
William E CopelandUniversity of Vermont, Burlington, Vermont.
Michael J MeaneyMcGill University, Montreal, Quebec, Canada.
Ian H GotlibStanford University, Stanford, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Resilience in psychiatry is often defined as the absence of psychopathology following early adversity. Resilience may be better operationalized as a continuous construct reflecting the degree to which individuals are functioning better than would be predicted given their adversity exposure. We used a continuous metric of resilience to predict mental health problems in 2 richly phenotyped samples studied longitudinally, and compared findings to those of conventional grouping approaches. Method: Exposure to early adversity was assessed at baseline (Study I: N = 1,265; Study II: N = 191), and mental health was assessed several times over a decade (9-21 years of age). Resilience was defined as the residual of participants' mental health symptoms accounting for early adversity. We then used generalized additive models to examine mental health symptoms across adolescence as a function of resilience to adversity. Finally, we compared continuous approaches with grouping approaches to assess resilience. Results: In both studies, greater resilience to adversity in childhood predicted fewer mental health problems in adolescence. Although both approaches to modeling resilience predicted unique variance in subsequent mental health symptoms when modeled simultaneously, the grouping approaches identified fewer individuals as resilient than did the continuous approach. Conclusion: A continuous approach to operationalizing resilience significantly predicted mental health symptoms across adolescence. Furthermore, both continuous and categorical operationalizations predicted unique variance in mental health outcomes. Importantly, however, grouping approaches may overlook a significant number of individuals who are, by a continuous assessment, resilient. Determining the optimal approach for identifying resilient individuals should be a priority for mental health research.

Indexed as

adolescenceearly adversitylongitudinal studymental healthresilience

Identifiers

PMID42220638
PMCPMC13221814

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.