Evidence map›Paper›PMID 42220617›Full record

ArticleFrontiers in network physiology2026

Mesenteric perfusion at rest and during feeding in healthy children.

Kathryn E Tobert, Kathryn Higdon, Theresa A Mikhailov, John P Scott, Wendi Redfern, George M Hoffman

Abstract read
In one paragraph

Article in Frontiers in network physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kathryn E TobertMedical College of Wisconsin, Milwaukee, WI, United States.
Kathryn HigdonDivision of Critical Care, Department of Pediatrics, University of Missouri Health Care, Columbia, MO, United States.
Theresa A MikhailovDivision of Critical Care, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, United States.
John P ScottPediatric Intensive Care Unit, Children's Wisconsin, Milwaukee, WI, United States.
Wendi RedfernPediatric Intensive Care Unit, Children's Wisconsin, Milwaukee, WI, United States.
George M HoffmanPediatric Intensive Care Unit, Children's Wisconsin, Milwaukee, WI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In critical illness, mesenteric organs are at risk for ischemic injury. Near infrared spectroscopy (NIRS) measures an index of regional venous-weighted tissue oxyhemoglobin saturation, an approximation of regional oxygen supply-demand economy. Mesenteric NIRS measures have been utilized in critically ill neonates to monitor for necrotizing enterocolitis but have not been well-described in healthy infants or children. The purpose of this study was to provide preliminary estimates of normal values for mesenteric regional saturations in healthy infants and young children during activities including feeding. Methods: We enrolled healthy infants and children between 1 month and 6 years for this observational study. Regional oxygen saturation (rSO Results: Nineteen subjects (age 33.8 ± 20.7 months, weight 13.5 ± 4.7 kg [mean ± SD]) completed the study. Absolute rSO Conclusion: In this study of healthy infants and young children, we observed small reductions in mesenteric rSO

Indexed as

enteral nutritionmesenteric perfusionnear infrared spectroscopynetwork physiologypediatricsregional oxygen delivery

Identifiers

PMID42220617
PMCPMC13215819

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.