Evidence map›Paper›PMID 42220475›Full record

ArticleJournal of pediatrics, perinatology and child health2026

Closing the Gap Between Recommendation and Uptake: Provider Communication About Low-Dose Aspirin for Preeclampsia Prevention.

Sharla M Smith, Shea Kempsen, Claire Metcalf, Oluoma Obi, Elizabeth Madrigal, Kionna L Henderson, Megha Ramaswamy

Abstract read
In one paragraph

Article in Journal of pediatrics, perinatology and child health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sharla M SmithUniversity of Kansas Medical Center, Kansas City, KS, USA.
Shea KempsenUniversity of Kansas Medical Center, Kansas City, KS, USA.
Claire MetcalfUniversity of Kansas Medical Center, Kansas City, KS, USA.
Oluoma ObiUniversity of Kansas Medical Center, Kansas City, KS, USA.
Elizabeth MadrigalUniversity of Kansas Medical Center, Kansas City, KS, USA.
Kionna L HendersonResearch Scientist II, Health and Wellness Center, Baylor Scott & White Health and Wellness Center, 4500 Spring Avenue, Dallas, TX 75210, USA.
Megha RamaswamyProfessor and Chair, Department of Health Systems and Population Health, School of Public Health, University of Washington, Seattle, WA, USA.

Funding

Improving the Quality of Prenatal Care for Low-Income, Urban, Black WomenK01HL149977 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SMITH, SHARLA ANNETTE · 2020 to 2024
$701k
NHLBI NIH HHS K01 HL149977
6 · The paper itself

Abstract

Introduction: Hypertensive disorders of pregnancy (HDPs), including preeclampsia, disproportionately contribute to preventable maternal morbidity and mortality. This study examined variations in clinician counseling and management of HDPs, provider communication about low-dose aspirin (LDA) prophylaxis, and barriers and facilitators to patient activation. Methods: A cross-sectional, mixed-methods study was conducted with perinatal care providers at two Midwest academic medical centers (2021-2022). An online survey was completed by 74 providers, followed by semi-structured interviews with a purposive sample of 13 providers. Survey data were analyzed descriptively using SAS 9.4; interview transcripts were analyzed using deductive thematic analysis with intercoder reliability. Results: All interviewed providers recommended LDA initiation between 12- and 16-weeks' gestation. Primary barriers included limited medication adherence (43%) and appointment non-attendance (16.5%). Facilitators included LDA's low cost, over-the-counter availability, and established safety profile. Themes include initiating conversations about LDA with all patients regardless of risk, emphasizing universal LDA uptake, and recognizing continued preeclampsia risk postpartum. Conclusions: Providers demonstrated familiarity with HDP guidelines but exhibited inconsistencies in counseling. Reframing "patient compliance" as "patient activation" supports equity-centered shared decision-making. Recommended strategies include establishing universal LDA recommendation protocols, expanding Medicaid coverage to reduce insurance barriers, and implementing community-focused public health education initiatives.

Indexed as

Hypertensive disordersMaternalPreeclampsiaPregnancyUnited StatesWomenWorldwide

Identifiers

PMID42220475
PMCPMC13218739

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.