ArticleJournal of oral & facial pain and headache2026
Qualitative validation of TnED©, an electronic instrument capturing pain dimensions in patients with trigeminal neuralgia.
Article in Journal of oral & facial pain and headache, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06019338 (A Study to Validate a Diary Developed by Noema Pharma That Will be Used for Future Trigeminal Neuralgia Clinical Research Studies to Capture Pain Dimensions.), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Study to Validate a Diary Developed by Noema Pharma That Will be Used for Future Trigeminal Neuralgia Clinical Research Studies to Capture Pain Dimensions.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundTrigeminal neuralgia (TN) is a severe episodic facial pain that has a significant impact on mood and activities of daily living. To accurately measure pain in TN, patient diaries need to be specifically developed to capture dimensions of pain in both TN phenotypes (
methodsParticipants were divided into two groups: those with purely paroxysmal pain and those with paroxysmal and concomitant continuous pain; each group was provided with a data collection instrument (diary) specific to their TN phenotype. Participants completed the instrument daily for 14 days. A qualitative, semi-structured interview was conducted to collect feedback on the instrument.
resultsA total of 30 participants were enrolled in 2 English-speaking countries (USA, UK). Nearly all participants stated that the items were clear and easy to understand, relevant, measured all symptoms of the condition, and had a suitable recall period and response options. Some participants suggested additional items to be collected. Most participants regarded pain severity as the most important concept due to its debilitating impact on their lives. Few changes to the instrument were suggested, and the study sponsor decided not to implement any of the proposed changes.
conclusionsOverall, the Trigeminal Neuralgia Electronic Diary was well-received and can be used to measure symptoms of TN in clinical trials or in a clinical setting. Psychometric validation of the TnED© instrument is ongoing. CLINICAL
trial registrationNCT06019338, retrospectively registered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.