Evidence map›Paper›PMID 42220246›Full record

ReviewAnatomy & cell biology2026

Fluoride enamel stability and remineralization.

Junseo Lee, Minsoo Kang, Cal Thomas Wenninger, Jiayun Li, Sophia Hattie Wirtz, Lauren Kim, Dhanvi Kanade, Madeline Lee Dahlk, Rana Essa

Abstract readReview
In one paragraph

Review in Anatomy & cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junseo LeeUniversity of Wisconsin-Madison, College of Agricultural & Life Sciences, Madison, WI, USA.ORCID https://orcid.org/0009-0000-1929-6583
Minsoo KangUniversity of Toronto, Faculty of Arts and Sciences, Toronto, ON, Canada.ORCID https://orcid.org/0009-0004-9156-4334
Cal Thomas WenningerUniversity of Wisconsin-Madison, College of Agricultural & Life Sciences, Madison, WI, USA.ORCID https://orcid.org/0009-0001-6686-5096
Jiayun LiUniversity of Wisconsin-Madison, College of Agricultural & Life Sciences, Madison, WI, USA.ORCID https://orcid.org/0009-0004-5657-0085
Sophia Hattie WirtzUniversity of Wisconsin-Madison, College of Agricultural & Life Sciences, Madison, WI, USA.ORCID https://orcid.org/0009-0001-0400-360X
Lauren KimCase Western Reserve University, College of Arts and Sciences, Cleveland, OH, USA.ORCID https://orcid.org/0009-0004-6412-5168
Dhanvi KanadeUniversity of Wisconsin-Madison, College of Agricultural & Life Sciences, Madison, WI, USA.ORCID https://orcid.org/0009-0005-6262-3056
Madeline Lee DahlkUniversity of Wisconsin-Madison, College of Agricultural & Life Sciences, Madison, WI, USA.ORCID https://orcid.org/0009-0001-7259-6937
Rana EssaUniversity of Wisconsin-Madison, College of Agricultural & Life Sciences, Madison, WI, USA.ORCID https://orcid.org/0009-0005-8664-883X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental caries remains as one of the most prevalent noncommunicable diseases even with advances in preventive dental care. This literature-based research examines how fluoride exposure influences enamel stability and caries formation. We hypothesized that fluoride reduces caries incidence by promoting remineralization and reinforcing the crystal lattice structure. A comprehensive search was done through PubMed, ScienceDirect, Karger, and Figshare to select peer reviewed studies that evaluated fluoride and enamel interactions. Quantitative data were extracted from open access

Indexed as

ApatitesBacteriaDental enamelEndodonticsFluorides

Identifiers

PMID42220246
PMCPMC13616762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.