Evidence map›Paper›PMID 42220047›Full record

ArticleUltrasonography (Seoul, Korea)2026

Super-resolution contrast-enhanced ultrasound: recent advances.

Yunlin Huang, Rui Cheng, Ying Wang, Yi Dong, Jeong Min Lee

Abstract read
In one paragraph

Article in Ultrasonography (Seoul, Korea), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunlin HuangDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Rui ChengDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ying WangDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi DongDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jeong Min LeeDepartment of Radiology, Seoul National University Hospital, Seoul, Korea.

Funding

Deutsche Forschungsgemeinschaft M-0504National Natural Science Foundation of China 82071942
6 · The paper itself

Abstract

Super-resolution (SR) contrast-enhanced ultrasound (CEUS) is a novel sub-diffraction imaging modality that surpasses the diffraction limitations of conventional ultrasound and enables visualization of intricate microvascular architectures. SR CEUS provides improved quantification of hemodynamics and enhanced visualization of microvessels, thereby overcoming several inherent limitations of traditional CEUS. Initially demonstrated for imaging microvessels in the brains of small animals, SR CEUS has subsequently been investigated in multiple fields, including oncology, nephrology, and neurological research, with applications reported in breast cancer, chronic liver disease, and lymph node evaluation. However, clinical translation remains limited by prolonged acquisition times resulting from suboptimal microbubble detectability and the requirement for diluted contrast agents. This review summarizes the technical principles, clinical applications, current limitations, and future directions of SR CEUS from a clinical perspective.

Indexed as

HemodynamicsMicrobubblesMicrovesselsSuper-resolution contrast-enhanced ultrasoundUltrasound localization microscopyVisualization

Identifiers

PMID42220047
PMCPMC13246927

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.