Evidence map›Paper›PMID 42220029›Full record

Trial reportJournal of musculoskeletal & neuronal interactions2026

Impact of Sensory Re-education Paradigm on Quality of Life, Tactile Sensation, and Proprioceptive Acuity in Patients with Post-COVID-19 Polyneuropathy: A Randomized Controlled Trial.

Hossam M Alsaid, Younes A Khadour, Hoda M Zakaria, Ebtesam M Fahmy, Fater A Khadour, Rehab S Mamoon, Azza S A Khalil, Walaa M Ragab, Ashraf A Darwesh, Mohamed G Ali

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC
In one paragraph

Trial report in Journal of musculoskeletal & neuronal interactions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05911113 (Impact Of Sensory Re-Education Paradigm On Sensation And Quality Of Life In Patients Post-Covid 19 Polyneuropathy), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05911113 nacompletednot on this map

Impact Of Sensory Re-Education Paradigm On Sensation And Quality Of Life In Patients Post-Covid 19 Polyneuropathy

TypeinterventionalSponsorCairo UniversityRan2023 to 2023Enrolled40ConditionsPost-COVID-19 SyndromeArmssensory re-education training, traditional treatment
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hossam M AlsaidDepartment of Physical Therapy for Neurology and Neurosurgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Younes A KhadourDepartment of Physical Therapy for Neurology and Neurosurgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Hoda M ZakariaDepartment of Physical Therapy for Neurology and Neurosurgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Ebtesam M FahmyDepartment of Neurology, Kasr Al-Aini, Faculty of Medicine, Cairo University, Egypt.
Fater A KhadourDepartment of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Rehab S MamoonDepartment of Physical Therapy for Women's Health, Faculty of Physical Therapy, South Valley (Qena) University, Qena, Egypt.
Azza S A KhalilDepartment of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, Saudi Arabia.
Walaa M RagabDepartment of Physical Therapy, College of Medical Rehabilitation Sciences, Taibah University, Saudi Arabia.
Ashraf A DarweshDepartment of Physical Therapy for Neurology and Neurosurgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Mohamed G AliDepartment of Physical Therapy for Women's Health, Faculty of Physical Therapy, South Valley (Qena) University, Qena, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study evaluated the effect of sensory re-education on quality of life and sensation in patients with post-COVID-19 polyneuropathy.

methodsForty patients with post-COVID-19 polyneuropathy were randomly assigned to a study group (Group A) or a control group (Group B), each with 20 participants. Group A received a sensory re-education protocol plus the traditional physiotherapy, including proprioceptive neuromuscular facilitation (PNF) and strengthening exercises for wrist extensors, hand grip, and thumb opposition. Group B received the traditional physiotherapy alone. Both groups were treated for one hour, three times weekly, for six weeks. Quality of life was assessed using the Arabic WHOQOL-BREF. Tactile sensation was assessed using the Semmes-Weinstein Monofilament (SWM) test, and proprioception via the laser-pointer angle reproduction test (LP-ART). Assessments were performed pre- and post-intervention.

resultsBoth groups showed significant pre- to post-treatment improvements in quality of life, proprioception, and tactile sensation (p≤ 0.05). Group A demonstrated significantly greater gains in quality of life and proprioception compared to Group B (p≤ 0.05), but no statistically significant difference between groups in tactile sensation (p> 0.05).

conclusionSensory re-education, when integrated into traditional physiotherapy, significantly improves quality of life and proprioception in post-COVID-19 polyneuropathy but does not significantly affect tactile sensation. These findings support incorporating sensory re-education into rehabilitation protocols to enhance functional outcomes in this population. CLINICALTRIALS: gov ID: NCT05911113.

Indexed as

COVID-19Physical Therapy ModalitiesPolyneuropathiesProprioceptionQuality of LifeTouchAdultAgedFemaleHumansMaleMiddle AgedPost-Acute COVID-19 SyndromeDeep SensationPost-COVID-19 PolyneuropathyQuality of LifeSensory RehabilitationTactile Sensation

Identifiers

PMID42220029
PMCPMC13223784

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.