Evidence map›Paper›PMID 42219971›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026

Imaging the interaction of astrocytes and neurons.

Karl Herholz

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Karl HerholzDivision of Neuroscience, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID 0000-0002-8658-0151

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular imaging of the interaction between astrocytes and neurons in humans is an important yet challenging task. While previous studies indicated that activation of astrocytes may contribute to the loss of neurons, the paper by Crine et al. in this issue found the opposite, a corresponding decline of imaging markers for astrocytes and dopaminergic neurons. This is a comment on the limitations and future perspectives for research on the interaction between glia and neuronal survival in aging and neurodegenerative diseases in humans.

Indexed as

AstrocytesDopaminergic NeuronsMolecular ImagingNeuronsAgingAnimalsHumansNeurodegenerative DiseasesAgingastrocytesdopaminergic neuronsmolecular imagingpositron emission tomography

Identifiers

PMID42219971
PMCPMC13350070

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.