Evidence map›Paper›PMID 42219815›Full record

ArticlePlant, cell & environment2026

CsSPX-PHR/PHL-PHT1 and CsmiR399a-PHO2-PHT1/PHO1 Modules Orchestrate Pi Use Efficiency and Aluminium Tolerance in Tea Plants.

Hongjie Liu, Jiaojiao Liu, Weiming Hu, Meng Yang, Jingyi Zhou, Anqi Peng, Tianmei Long, Ping Li, Hao Zuo, Zhi Zhou and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hongjie LiuNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Jiaojiao LiuNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Weiming HuNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Meng YangNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Jingyi ZhouNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Anqi PengNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Tianmei LongNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Ping LiNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Hao ZuoNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Zhi ZhouCollege Agronomy, Hunan Agricultural University, Changsha, China.
Zhonghua LiuNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.
Jian ZhaoNational Research Center of Engineering and Technology for Utilisation of Botanical Functional Ingredients, Laboratory of Tea Science of Ministry of Education, College of Horticulture, Hunan Agricultural University, Yuelushan Laboratory, Changsha, China.ORCID https://orcid.org/0000-0002-4416-7334

Funding

Major Research and Development Project of Hunan Province 2025JK2023National Natural Science Foundation of China 32494780National Natural Science Foundation of China 32494782National Natural Science Foundation of China U23A20214Yuelushan Laboratory Breeding Project YLS-2025-ZY02021
6 · The paper itself

Abstract

High aluminium (Al) toxicity in acidic soils limits natural phosphate (Pi) nutrition to Al-hyperaccumulator tea plants, yet how they achieve Pi use efficiency (PUE) and Al tolerance remains elusive. Here, we deciphered Pi signalling networks and regulatory mechanisms underlying tea plant PUE, by functionally characterising Pi signalling components responding to Pi/N status changes and Al/H stress. CsPHT1.4 and CsPHT1.5 are PM-localised transporters expressed in tea root xylem and stem phloem for Pi uptake and redistribution. The physical interactions between CsSPX1a/2 and CsPHR1b/PHL1a under Pi supply repressed CsPHR1b/PHL1a activation of CsPHT1.4 transcription, but CsPHR1b/PHL1a were relieved from inhibition from the interactions for root Pi uptake under Pi deficiency or low Al conditions. Moreover, N-supply activated CsHHO6a suppressed CsSPX1a, and further activated CsPHR1b and CsPHT1.4 for Pi acquisition. High Al/H toxicity up-regulated CsSTOP1a/2a activated CsSPX1a transcription to repress CsPHR1b-CsPHT1.4 and inhibit Pi absorption and root growth. Meanwhile, Pi supply and high Al/H stress activated CsmiR399a to repress CsPHO2 and stabilise CsPHT1.5/CsPHO1 for Pi redistribution in tea plants. CsSPX1a-CsPHR1b-CsPHT1.4 and CsmiR399a-CsPHO2-CsPHT1.5 modules coordinately regulate Pi homoeostasis under Al/H stress and various N- and Pi- nutrition conditions, laying a foundation for genetic improvement of tea PUE and adaptation to stresses.

Indexed as

AluminumCamellia sinensisPhosphatesPlant ProteinsGene Expression Regulation, PlantPlant RootsSignal TransductionStress, PhysiologicalAluminumPhosphatesPlant Proteinsaluminium stressmiR399‐PHO2N supplyPi sensing and signallingSPX‐PHR‐PHT

Identifiers

PMID42219815
PMCPMC13436479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.