Evidence map›Paper›PMID 42219749›Full record

ArticleG3 (Bethesda, Md.)2026

Multimodal genomic prediction is not a buzzword: why modern plant breeding must integrate genomics, enviromics, and phenomics.

José Crossa, Abelardo Montesinos-López, Jaime Cuevas, Osval A Montesinos-López, Paulino Pérez-Rodríguez, Alison Bentley

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

José CrossaPrograma de Estadística y Ciencia de Datos, Colegio de Postgraduados, Montecillo Texcoco, Estado de México 56230, México.ORCID 0000-0001-9429-5855
Abelardo Montesinos-LópezCentro Universitario de Ciencias Exactas e Ingenierías (CUCEI), Universidad de Guadalajara, Guadalajara, Jalisco 44430, México.ORCID 0000-0002-0525-9973
Jaime CuevasDivisión de Ciencias, Ingeniería y Tecnologías (DCIT), Universidad Autónoma del Estado de Quintana Roo, Chetumal, Quintana Roo 77019, México.ORCID 0000-0002-0685-2867
Osval A Montesinos-LópezFacultad de Telemática, Universidad de Colima, Colima, Colima 28040, México.ORCID 0000-0002-3973-6547
Paulino Pérez-RodríguezPrograma de Estadística y Ciencia de Datos, Colegio de Postgraduados, Montecillo Texcoco, Estado de México 56230, México.
Alison BentleyCSIRO Agriculture and Food, Black Mountain, Canberra, ACT 2601, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant breeding has entered a new era, transitioning from a predominantly unimodal, genomics-focused paradigm to one defined by multimodal data integration. Dense genomic markers, long-term environmental datasets, physiological and omics measurements, and high-throughput phenotyping platforms are now routine components of modern breeding programs. Paradoxically, while plant breeding now operates in a multimodal data ecosystem, most prediction models remain effectively unimodal, relying on a single type of information at a time-genomics alone, enviromics alone, physiology alone, or phenomics alone. This overlooks a fundamental biological reality: complex traits emerge from the interaction of genetic potential, environmental conditions, and dynamic physiological responses. Across the life sciences, the integration of heterogeneous biological data has become a central strategy for improving prediction and discovery. We argue that genomic prediction must become truly multimodal to reflect the biological reality that complex traits emerge from interacting genetic, environmental, and physiological processes. We clarify multimodality as distinct from commonly conflated concepts such as multi-environment or multi-trait prediction and outline strategies for integrating heterogeneous data sources using multi-kernel and multi-stream modeling frameworks.

Indexed as

Genome, PlantGenomicsPhenomicsPlant BreedingPlantsGene-Environment InteractionPhenotypeQuantitative Trait Locienvironmentsgenomic predictionmultimodal

Identifiers

PMID42219749
PMCPMC13334170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.