ArticleThe clinical respiratory journal2026
Exercise-Induced Desaturation in COPD Patients Postexacerbation: Impact of Different Definitions on Prevalence Rates in a Rehabilitation Setting.
Article in The clinical respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundExercise-induced oxygen desaturation (EID) refers to a significant decrease in oxygen saturation (SpO
objectiveThe objectives of this study were to evaluate (a) the different definitions of EID reported in the literature, (b) the prevalence of EID during the 6-min walking test (6MWT) in a cohort of COPD patients undergoing pulmonary rehabilitation (PR), and (c) the agreement between the definitions.
methodsA scoping review was conducted to assess existing EID definitions. The prevalence of EID in a cohort of postexacerbation COPD patients performing the 6MWT at admission to PR was retrospectively evaluated based on selected definitions. Agreement between definitions was assessed using Fleiss' kappa.
resultsOf the 244 articles reviewed, 62 met the inclusion criteria, and 23 definitions of EID were identified. The seven most cited definitions found were applied to 954 patients who completed the 6MWT at admission. The most common criterion was a ≥ 4% decrease in SpO
conclusionsIn a large COPD cohort recovering from exacerbation, EID prevalence varied significantly depending on the definition used. Although good agreement was found between the criteria, the most conservative definition identified EID in only 15% of patients. Future studies will be necessary to determine which definition is most appropriate, predictive for outcomes, and useful for prescribing oxygen under effort.
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