Evidence map›Paper›PMID 42219568›Full record

ArticlePest management science2026

Methyl thiobutyrate: A microbial volatile compound with dual modes-of-action against root-knot nematodes.

Rui Liu, Luyao Zhu, Qian Chen, Jian Ling, Yuhong Yang, Qianqian Shi, Songyu Zhao, Xueliang Tian, Zhenchuan Mao, Jianlong Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rui LiuState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID https://orcid.org/0009-0000-4818-4935
Luyao ZhuState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Qian ChenState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Jian LingState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Yuhong YangState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Qianqian ShiShandong Engineering Research Center for Environment-Friendly Agricultural Pest Management, College of Plant Health and Medicine, Qingdao Agricultural University, Qingdao, China.ORCID https://orcid.org/0000-0002-3616-1485
Songyu ZhaoHenan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, China.
Xueliang TianHenan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, China.
Zhenchuan MaoState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-1035-7711
Jianlong ZhaoState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.

Funding

This research was supported by grants from the National Key R&D Program of China (2023YFD1400400; 2024YFD2300702), the National Natural Science Foundation of China (32172366; 32372508), the China Agriculture Research System (CARS-23), and the Qingdao Science and Technology Benefiting the People Demonstration Project (25-1-5-xdny-6-nsh).
6 · The paper itself

Abstract

backgroundRoot-knot nematodes (RKN; Meloidogyne incognita) cause severe losses in tomato production, driving the need for sustainable control strategies. Methyl thiobutyrate (MTB), a volatile organic compound produced by the biocontrol bacterium Bacillus cereus Bc-cm103, was investigated for its nematicidal activity and underlying modes-of-action (MoAs).

resultsMTB exhibits direct contact toxicity, with a 12-h median lethal concentration (LC₅₀) of 48 μg mL

conclusionMTB controls RKN through a dual MoA involving direct contact toxicity, fumigant activity and the induction of systemic resistance in plants. This multifaceted activity highlights MTB's significant potential as an eco-friendly nematicide for integrated nematode management. © 2026 Society of Chemical Industry.

Indexed as

Antinematodal AgentsBacillus cereusPlant DiseasesSolanum lycopersicumTylenchoideaVolatile Organic CompoundsAnimalsPlant RootsPlant Systemic Acquired ResistanceAntinematodal AgentsVolatile Organic Compoundsbiocontrolinduced resistanceMeloidogyne incognitamethyl thiobutyrate (MTB)mode‐of‐actionnematicidal activity

Identifiers

PMID42219568
PMCPMC13453241

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.